Less about game balance more about that whole CTE thing...
CTE is solved by eliminating kickoffs.
Elimintating kickoffs is a radical step that is probably not going to fly well with the fans or owners. It's a specialty position that's designed for big plays to happen. Unfortunately, Kickers have a lot of control, and penalizing touchbacks just encourages them to not kick into the end zone, as @Mr. E explained.
The rule change I'm most looking into is the automatic ejection rule. In many ways, it's a good thing, and it's smart that they applied it to unsportsmanlike conduct and not personal fouls, which can happen in the heat of the moment and usually are unintentional. Notably, Aqib Talib would've been ejected in the 3rd qtr of super bowl 50 this year. I remember when it happened because the rumors of the rule change were flying the week before the game.
"...to abolish any and all 'chop' style blocks." Chop blocks are a really big deal, as its something that's not very well enforced at the moment, especially at the WR position. If this is enforced, we will see changes similar to when the hands to the face rules became more enforced from the defensive line.
IR Boomerang really isn't a thing anymore. All players can return from IR after 6 weeks, which is a huge step forward for many players who had the ability to come back before they could.
Teams are also now being flagged for delay of game if they attempt to call a timeout illegally.
Receivers are also no longer penalized yardage for going out of bounds on their own power, coming back in, and making first contact with the ball. The penalty is just loss of down. This is actually a rather dumb change to me, since receivers can cause what are basically incompletions by just going out of bounds if they have no choice and an interception is imminent. This case is rather arbitrary, however.
Actually some decent rule changes this year. The kickoffs and automatic ejection are both experimental 1-year rule changes, which is a good thing since those are the ones whose effects are the most unclear. Looking forward to it.